刘子述

　　 　　

一、 个人简介

黑龙江省大庆人，祖籍山东海阳，中共党员。taptap国际服苹果版青年教授，博士生导师。曾入选国家建设高水平大学公派研究生项目攻读博士研究生、中国博士后国（境）外交流项目引进计划。长期从事环境微生物生理、生态方面理论与应用研究。发表SCI论文40余篇，H 指数17。其中以第一作者/通讯作者在Microbiome、Environmental Science & Technology等期刊发表论文8篇，2篇入选ESI高被引。担任国产期刊Environmental Science and Ecotechnology青年编委。

二、 教育与工作经历

2025.09-至今 taptap国际服苹果版，资源环境学院，青年教授

2021.01-2025.08 浙江大学，环境与资源学院，博士后

2019.07-2020.12 Helmholtz Centre for Environmental Research - UFZ， Department Environmental Microbiology，Scientific Technician

2013.09-2019.06 Universität Leipzig，Faculty of Life Sciences, Biology，PhD;Helmholtz Centre for Environmental Research - UFZ， Department Environmental Microbiology，Guest Researcher

2011.09-2013.07 哈尔滨工业大学，环境工程专业，硕士

2007.09-2011.07 哈尔滨工业大学，环境科学专业，学士

三、 研究兴趣

我的研究聚焦于人类世背景下环境微生物组的动态演化及其健康效应。通过整合生态学、进化生物学与公共卫生视角，我关注环境污染和气候变化如何重塑环境微生物群落及其功能网络，进而影响生态系统稳定性与人类健康。主要研究方向包括：

（1）环境变化驱动的微生物适应性演进及其健康风险；

（2）抗生素抗性在环境中传播的界面行为和生态原理；

（3）多组学分析方法与微生物流式细胞术的融合应用。

四、 主要参与科研项目

1. 胆汁酸化合物协同诱导微生物耐药性形成的机制研究，国家自然科学基金青年基金，主持，2023-2025

2. 环境中抗生素抗性基因扩增传播界面行为及其风险，国家自然科学基金重大项目课题，参与，2022-2025

3. 场地环境中抗生素与抗性基因的剂量-效应关系研究，国家重点研发计划课题，子课题主持，2020-2024

4. 中国博士后国（境）外交项目引进项目，主持，2021-2023

5. 中国博士后科学基金第73批面上资助，主持，2023-2024

6. 中国博士后科学基金第71批面上资助，主持，2022

五、 部分学术论文

1. Liu, Zishu; Yao, Xiangwu; Chen, Chengyi; Zhao, Yuxiang; Dong, Chifei; Sun, Lingtao; Zhao, Junxian; Zhang, Baofeng; Yv, Zhendi; Cheng, Dongqing, Zhu, Lizhong; Hu, Baolan*. Growth of microbes in competitive lifestyles promotes increased ARGs in soil microbiota: insights based on genetic traits. Microbiome, 2025, 13: 8（ESI高被引）

2. Ji, Youqi; Wang, Yinhuan; Xu, Zhangkai; Chen, Danlei; Yu, Zhendi; Shao, Qingyi; Hong, Xin; Liu, Zishu*; Cheng, Dongqing*. Small molecules from medicinal plant iris tectorum as histidine kinase inhibitor to resensitize β-lactam-resistant Escherichia coli, Molecules, 2025, 30(3): 663

3. Tang, Huiming; Liu, Zishu; Hu, Baolan; Zhu, Lizhong*. D-ring modifications of tetracyclines determine their ability to induce resistance genes in the environment. Environ Sci Technol, 2024, 58 (2): 1338-1348

4. Dong, Chifei; Liu, Zishu; Zhu, Lin; Zhang, Baofeng; Chi, Taolve; Yu, Zhendi; Zhou, Meng; Sun, Lingtao; Zhao, Yuxiang; Zhu, Lizhong; Hu, Baolan*. Dynamic migration and risk of cephalosporin antibiotic resistance genes: Move from pharmaceutical plants through wastewater treatment plants to coastal tidal flats sediments. Water Res, 2024, 261: 121983

5. Liu, Zishu; Zhao, Yuxiang; Zhang, Baofeng; Wang, Jiaqi; Zhu, Lizhong; Hu, Baolan*. Deterministic effect of pH on shaping soil resistome revealed by metagenomic analysis. Environ Sci Technol, 2023, 57 (2): 985-996（ESI高被引）

6. Liu, Zishu; Jin, Yihao; Yu, Zhendi; Liu, Zhengzheng; Zhang, Baofeng; Chi, Taolv; Cheng, Dongqing; Zhu, Lizhong; Hu, Baolan*. Vertical migration and dissipation of oxytetracycline induces the recoverable shift in microbial community and antibiotic resistance. Sci Total Environ, 2023, 905: 167162

7. Zhao, Yuxiang; Liu, Zishu; Zhang, Baofeng; Cai, Jingjie; Yao, Xiangwu; Zhang, Meng; Deng, Ye; Hu, Baolan*. Inter-bacterial mutualism promoted by public goods in a system characterized by deterministic temperature variation. Nat Commun, 2023, 14 (1): 5394（ESI高被引）

8. Li, Shuang; Abdulkadir, Nafi’u; Schattenberg, Florian; Nunes da Rocha, Ulisses; Grimm, Volker; Müller, Susann*; Liu, Zishu. Stabilizing microbial communities by looped mass transfer. Proc Natl Acad Sci U S A, 2022, 119 (17): e2117814119

9. Xu, Zhangkai^#; Liu, Zishu^#; Chen, Jiang; Zou, Songyan; Jin, Yan; Zhang, Ronghua; Sheng, Yaqi; Liao, Ningbo; Hu, Baolan; Cheng, Dongqing*. Effect of direct viral-bacterial interactions on the removal of norovirus from lettuce. Front Microbiol, 2021, 12: 731379

10. Liu, Zishu; Müller, Susann*. Bacterial community diversity dynamics highlight degrees of nestedness and turnover patterns. Cytometry Part A, 2020, 97 (7): 742-748

11. Liu, Zishu; Cichocki, N.; Hübschmann, T.; Süring, C.; Ofiteru, I. D.; Sloan, W. T.; Grimm, V.; Müller, S*. Neutral mechanisms and niche differentiation in steady-state insular microbial communities revealed by single cell analysis. Environ Microbiol, 2019, 21 (1): 164-181

12. Liu, Zishu^#; Cichocki, N.^#; Bonk, F.; Günther, S.; Schattenberg, F.; Harms, H.; Centler, F.; Müller, S*. Ecological stability properties of microbial communities assessed by flow cytometry. mSphere, 2018, 3 (1): e00564-00517

六、 研究生招生

硕、博研究生招生：欢迎对微生物学和环境科学感兴趣的同学报考，招生方向为环境科学（083001）、资源微生物学（0903Z2）。

七、 联系方式

邮箱：liuzishu@nwafu.edu.cn

地址：陕西杨凌taptap国际服苹果版（南校区）资源环境学院216室